Copyright © 2004 Cascade BioScience, Inc. All rights reserved.
| Description | Catalog # | Vial Size | Price (USD) |
| Anti-Human FANCC, clone 8F3 | ABM-6204 | 100 ug | $295 |
|
Western Blot:
|
1-5 micrograms/ml for cells over expressing FANCC |
|
Immunoprecipitation:
|
5-10 micrograms per 2 mg/ml sample to IP Flag-tagged FANCC |
| Immunofluorescence: | recommended; see figure |
|
Reactivity:
|
human |
|
Specificity:
|
recognizes wild type FANCC; 63 kDa; does not detect mutant form L554P |
|
Immunogen:
 |
synthetic peptide corresponding to amino acids 546-558 of human FANCC |
|
Host/Ig Type:
|
mouse monoclonal IgG2b |
|
Purification:
|
protein A chromatography |
|
Quality Control:
|
by WB of FANCC on overexpressing cell lines |
|
Liquid Carrier:
|
phosphate buffered saline |
|
Storage:
|
-20˚C |
|
Stability:
|
2 years |
Heinrich, M. C., Silvey, K. V., Stone, S., Zigler, A. J., Griffith, D. J., Montalto, M., Chai, L., Zhi, Y. and Hoatlin, M. E. “Post transcriptional cell cycle-dependent regulation of human FANCC expression”. Blood 95:3970-3977, 2000.
Hoatlin, M. E., Zhi, Y., Ball, H., Silvey, K., Melnick, A., Stone, S., Arai, S., Hawe, N., Owen, G., Zelent, A. and Licht, J. D. “A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF”. Blood 94:3737-3747, 1999
Xie, X., de Winter, J. P., Waisfisz, Q., Nieuwint, A., Scheper, R., Arwert, F. M., Hoatlin, M. E., Ossenkoppele, A., Schuurhuis, G. and Joenje, H. “Aberrant Fanconi anemia protein profiles in acute myeloid leukemia cells.” Br. J. Hematology 111:1057-1064, 2000.
