Literature Request | Mailing List | E-Mail New Product Newsletter | Lab Protocols and Procedures
Product Application References | Technical Support | Customer Service | How to Order
Contact Us 

Copyright © 2005 Cascade BioScience, Inc. All rights reserved.

Description Catalog # Vial Size Price (USD)
Anti-Human Phospho-IRS-2 (pSer731), polyclonal ABP-6022 100 ug $295
Research Applications
Antibody Characteristics
InfoSheet PDF
Western Blot:
0.5 -2.0 micrograms/ml

3-5 micrograms/sample derived from 1 x 107 cells

0.1-1 micrograms/ml
human; predicted mouse, rat

specific for human IRS-2 phosphorylated at the position of Serine 731 as demonstrated by dot blot assay using synthetically prepared IRS peptides; does not recognize other phosphorylated sites or non-phosphorylated IRS1 or IRS-2; band is abolished by the depletion of the phosphorylated specific synthetic peptide

synthetic peptide (YKASpSPAESS) corresponding to amino acids 727-736 of human IRS-2 at the phosphorylated site of Serine 731
Host/Ig Type:
rabbit polyclonal IgG
peptide affinity purification
Quality Control:
by immunoblot analysis on serum-treated mouse fibroblast extracts
Liquid Carrier:
phosphate buffered saline (pH 7.4) containing 0.02% sodium azide
2 years
About IRS
General References

1. Sun XJ et al (1991) Nature 352: 73-77
2. Sun XJ et al (1995) Nature 377: 173-177
3. Mothe I et al (1996) J Biol. Chem. 271: 11222-11227
4. Lavan BE et al (1997) J Biol. Chem. 272: 11439-11443
5. Lavan BE e al (1997) J Biol. Chem. 272: 21403-21407
6. Liu YF et al (2001) J Biol. Chem. 276 (17): 14459-14465
7. White MF (1998) Mol. Cell. Biochem. 182: 3-11


3T3 cell lysate IP'd with Anti-Human Phospho-IRS-2 (pSer731), polyclonal (ABP-6022) and subsequently probed with the same antibody